Name | 9-Methoxycamptothecine |
Synonyms | 11-Methoxycamptothecin 9-Methoxycamptothecine Methoxycamptothecin, 9- (S)-9-Methoxy Camptothecin (S)-9-METHOXY CAMPTOTHECIN (4S)-4-Ethyl-4-hydroxy-10-methoxy-1H-pyrano[3',4' |
CAS | 39026-92-1 |
Molecular Formula | C21H18N2O5 |
Molar Mass | 378.38 |
Density | 1.50±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 223-225℃ |
Boling Point | 773.1±60.0 °C(Predicted) |
Appearance | Yellow powder |
pKa | 11.20±0.20(Predicted) |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | Pale yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the Stinky Mappia feotida Miers Stalk Apocynaceae Ervatamia heyneana(Wall.)T.Cook. |
Reference Show more | 1. Jianquan, Peng Shuhong, LV Hanqing, Liu Huina, Zhu Junyi. Spectroscopic studies on the interaction between 9-methoxycamptothecin and BSA [J]. Chemical Research and Application 2020 v.32(07):32-38. |
biological activity | 9-Methoxycamptothecin (MCPT), isolated from Nothapodytes foetida, anti-tumor activity is exerted by inhibition of topoisomerase. 9-Methoxycamptothecin (MCPT) has a potent effect of inducing apoptosis in G2/M phase cells and cancer cells. |
Target | Topoisomerase. Apotosis. |
Chemical properties | light yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, arbuscular Mappia feotida Miers' stem, which is a plant of the family Acanthaceae, acanthopogonaceae, erratamia heynana (Wall.)T.Cook. |
Use | 9-methoxycamptothecin has anti-cancer effects. for content determination/identification/pharmacological experiments, etc |